Study of T-cell immunity, interferogenesis, inflammatory mediators in children with Varicella zoster virus infection

The aim of the study . Determination immune response mediators in patients with infection caused by Varicella Zoster virus various clinical and laboratory parameters. Materials methods. VZV DNA polymerase reaction method. blood content proinflammatory was assessed using ELISA method monoclonal antibodies (Protein contour, Petersburg). Research result. In INF- α , γ CD-8+ significantly lower than a typical form disease. course disease, less often determined. Discussion pustular chickenpox, level IL-1 β CD-4+ disease Conclusions A decrease indicators cellular immunity children chickenpox is an indication for vaccination.